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KMID : 0366220090440040294
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Korean Journal of Hematology
2009 Volume.44 No. 4 p.294 ~ p.297
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A Case of Vancomycin-Induced Thrombocytopenia
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Lee Jae-Hyeon
Cho Yong-Gon
Kim Dal-Sik
Lee Hye-Soo
Choi Sam-Im
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Abstract
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Immune thrombocytopenia is a rare complication associated with vancomycin. A 76-year-old male patient who was treated with vancomycin experienced severe thrombocytopenia and refractoriness as a result of platelet transfusion. Vancomycin-dependent antibodies in his thrombocytopenic serum were detected by flow cytometric analysis. The mechanism of thrombocytopenia is probably related to immunological destruction, as strongly suggested by its association with a specific drug-dependent anti-platelet antibody. (Korean J Hematol 2009;44:294-297.)
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KEYWORD
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Thrombocytopenia, Vancomycin, Drug-induced
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